Clinical study on treatment of rheumatoid arthritis of cold dampness obstruction and kidney yang qi deficiency with Juanbi granulae
10.3760/cma.j.issn.1673-4246.2012.02.009
- VernacularTitle:蠲痹颗粒用于寒湿痹阻和肾气虚寒型类风湿关节炎的临床疗效观察
- Author:
Shikui CUI
- Publication Type:Journal Article
- Keywords:
Juanbi granulae;
Cold dampness obstruction and kidney yang qi deficiency syndrome;
Rheumatoid arthritis
- From:
International Journal of Traditional Chinese Medicine
2012;34(2):122-125
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of Juanbi granulae on rheumatoid arthritis belonging to cold dampness obstruction and kidney yang qi deficiency syndrome.Methods All 120 RA patients in accordance with the inclusion criteria were divided into a 80 cases of study group,and a 40 cases of control group,by random table method.Methotrexate,10mg once a week,was given orally,as a basis for treatment.The treatment group given Juanbi granulae,15g for each time,3 times a day; while the control group was Zhenqingfengtongning sustained-release tablets,60mg for each time,twice daily.Both groups have adopted a one-month course of treatment.Statistics effect was evaluated after 4-week course of treatment.Results ①There was significant difference between the two group in terms of therapeutic effects and symptom effects after the treatment (the total effective rate of study group and control group was 100.0％,86.7％,U value was-4.071,-3.232 respectively,P＜0.05).② The treatment effects and the symptom effect of the cold dampness syndrome and the kidney yang qi deficiency syndrome in the same group showed statistical difference after the treatment (the total effective rate of study group and control group was 88.0％,80.0％,The U value of treatment effect was-5.50,-3.67 respectively,P＜0.01 or P＜0.05).(U value of syndrome effect was-2.909,-3.992 respectively,P＜0.05).③ Study group of after treatment ESR (17.05±7.15) mm/h,RF (32.46± 14.22) U/L,compared with the control group of after treatment,the difference was statistically significant (P＜0.05).Conclusion Juanbi granulae was effective in treating rheumatoid arthritis of both kidney yang qi deficiency syndrome and cold dampness obstruction syndrome,the effects were especially better for cold dampness obstruction syndrome.
