p21 activated kinase 4 and tumor
10.3760/cma.j.issn.1673-422X.2012.01.005
- VernacularTitle:p21活化激酶4与肿瘤的研究进展
- Author:
Lifang HE
;
Guojun ZHANG
- Publication Type:Journal Article
- Keywords:
p21 activated kinase 4;
Neoplasms;
Cell cycle
- From:
Journal of International Oncology
2012;39(1):15-18
- CountryChina
- Language:Chinese
-
Abstract:
p21 activated kinase 4 (PAK4) is a member of a family of serine/threonine kinase.PAK4plays an important role in a variety of cellular functions including cell cycle,cell proliferation,apoptosis,and cytoskeletal reorganization.Recently,PAK4 has been shown to overexpress in a variety of malignancies,and contribute to cancer cell migration and invasion through multiple signalling pathways.
