Visual imaging of quantum dots for in vivo malignancy cancer

VernacularTitle:量子点对体内恶性肿瘤可视化成像研究
Author: Yuan CAO ; Kai YANG
Publication Type:Journal Article
Keywords: Quantum dots; Neoplasms; Diagnostic imaging
From: Journal of International Oncology 2012;39(1):24-27
CountryChina
Language:Chinese
Abstract: Quantum dots (QD),a kind of nanocrystal,are made from Ⅱ-Ⅵ or Ⅲ-Ⅴ group elements.It has been reported that compared with current conventional fluorescent markers,QD have excellent optical properties such as strong fluorescence,photochemical stability and can be used for simultaneous multi-channel imaging.Meanwhile,as nanoparticle,QD can be easily surface modified with a variety of biological molecular and can reach cancer cells easily by penetrating the tumor angiogenesis.Therefore,QD have unique advantages in targeted real-time visual imaging of in vivo tumor and have great prospects in the individual diagnosis and treatment of tumor.However,the long-term biosafety after QD into the body still needs further study.