Studies on the Chemical Constituents from the Seeds of Zizyphus jujuba var. inermis.
10.20307/nps.2017.23.4.258
- Author:
Nam Kyung LEE
1
;
Hyun Jung SHIN
;
Wan Seok KIM
;
Gyo IN
;
Chang Kyun HAN
Author Information
1. R&D Headquarters, Korea Ginseng Corp., Daejeon 34128, Republic of Korea. leenamkyung@kgc.co.kr
- Publication Type:Original Article
- Keywords:
The seed of Zizyphus jujuba var. inermis;
3-pentadecylcatechol;
Anti-proliferative effect;
Anti-microbial activity;
Anti-oxidant effect
- MeSH:
Antioxidants;
Chloroform;
Medicine, Chinese Traditional;
Methanol;
Oleanolic Acid;
Stigmasterol;
Water;
Ziziphus*
- From:Natural Product Sciences
2017;23(4):258-264
- CountryRepublic of Korea
- Language:English
-
Abstract:
This study analyzed the seeds of Zizyphus jujuba var. inermis commonly used as a remedy in traditional Chinese medicine, in order to determine its various biologically active compounds. Through process 3-pentadecylcatechol, ρ-menth-8-ene, and γ-bisabolene were isolated and identified for the first time which are urushiol, monoterpenoidal, and sesquiterpenoidal compounds, respectively. Also, found were another sesquiterpenoidal compounds, vomifoliol, and four steroidal compounds, β-sitosterol, stigmasterol, stigmasta-5,23-dien-3β-ol, and stigmast-4-en-3-one. In addition, fourteen triterpenoidal compounds were isolated and identified. These were lupeol, betulinic acid, betulinaldehyde, alphitolic acid, 3-O-cis-ρ-coumaroyl-alphitolic acid, 3-O-trans-ρ-coumaroylalphitolic acid, 2-O-cis-ρ-coumaroyl-alphitolic acid, 2-O-trans-ρ-coumaroyl-alphitolic acid, zizyberanalic acid, ceanothic acid, oleanolic acid, maslinic acid, 3-O-cis-ρ-coumaroyl-maslinic acid, and 3-O-trans-ρ-coumaroylmaslinic acid. The structures were identified by comparing of the spectroscopic experiments, NMR and MS, and then compared that reported data, respectively. Three extracts of water, methanol, and chloroform from the seeds showed a weak anti-proliferative effect, anti-microbial activity, and anti-oxidant effect, respectively.
