A correlation analysis on the pulse wave velocity, ankle-brachial index and carotid atherosclerosis in type-2 diabetes
10.3760/cma.j.issn.1008-6315.2012.02.027
- VernacularTitle:2型糖尿病患者脉搏波传导速度、踝臂指数和颈动脉粥样硬化的相关性研究
- Author:
Xuepeng LIU
;
Chaofu ZHANG
- Publication Type:Journal Article
- Keywords:
Diabetes;
Arteriosclerosis;
Pulse wave velocity;
Ankle-brachial index;
Carotid artery membrane thickness
- From:
Clinical Medicine of China
2012;28(2):185-188
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the correlation of arterial compliance and carotid atherosclerosis in patients with type-2 diabetes.Methods Eighty cases of type-2 diabetic patients and 80 control subjects were recruited into the study.Brachial-ankle pulse wave velocity(BaPWV)and ankle-brachial index(ABI)were measured with atherosclerosis diagnostic devices VP-1000.The inner-membrane and medium-membrane thickness(IMT)of the common carotid artery and plaque were detected with color Doppler ultrasound.The difference of the pulse wave velocity in the subjects with carotid plaques were compared between the two groups.The correlations of carotid IMT with BaPWV and ABI were also analyzed.Results In the diabetic patients group,BaPWV([1752 ± 213]cm/s)was higher than that of normal control group([1279 ± 159]cm/s)(P ＜ 0.01);ABI in diabetic patients group(0.95 ± 0.13)was lower than that of control group(1.28 ± 0.17),(P ＜ 0.01).In the diabetic patients group,the incidences of carotid IMT thickening(45.0％)and plaques(35.0％)were both higher than that of control group(27.5％ and 10.8％,respectively)(P ＜ 0.05).In the diabetic patients group,the cases with carotid plaques had a higher BaPWV([1810 ± 296]cm/s)than those without([1480 ± 304]cm/s)(P ＜ 0.01).BaPWV was positively correlated with carotid IMT(r =0.271,P ＜ 0.05).ABI and IMT was negatively correlated(r =-0.406,P ＜ 0.05).Conclusion BaPWV and carotid IMT was positively correlated,while ABI and IMT was negatively correlated.BaPWV and ABI are indicators which are practicable and effective to evaluate the stiffness of peripheral arteries in patients with diabetes.
