The effect of C-reactive protein in assessing the disease severity and prognosis of community-acquired pneumonia
10.3760/cma.j.issn.1008-6315.2012.02.003
- VernacularTitle:C反应蛋白在社区获得性肺炎严重度及预后评估中的作用
- Author:
Shuai ZHANG
;
Hongxia ZHANG
;
Xiaohui LI
;
Zhenyang XU
- Publication Type:Journal Article
- Keywords:
Community-acquired pneumonia;
C-reactive protein;
Pneumonia severity index
- From:
Clinical Medicine of China
2012;28(2):119-121
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the changes of serum C-reactive protein(CRP)and pneumonia severity index(PSI)of community-acquired pneumonia(CAP)and further assess the effect of CRP on the severity and prognosis of CAP.Methods One hundred and six cases of patients with CAP hospitalized from January 2009 to May 2011 were retrospectively analyzed.Patients were classified according to different assessment criteria and age(≥65 years old)and serum CRP was detected in all patients.Results CRP was correlated positively with PSI(r =0.453,P ＜ 0.001).CRP and PSI had no correlation in elderly hospitalized patients with CAP,but CRP([81.70 ± 75.63]mg/L)correlated positively with PSI(78.30 ± 42.63)in non-elderly patients(r =0.489,P ＜ 0.001).There was significant difference on PSI(89.24 ± 36.44 vs 53.59 ± 35.41),CRP ([106.93 ±74.76]mg/L vs[31.34 ±33.68]mg/L)between PSI severity group and PSI non-severity group (t =-4.289,-5.934,respectively,P ＜ 0.001).Conclusion Both CRP and PSI can be used to evaluate the severity of community-acquired pneumonia,and CRP can be used as a supplement to PSI scoring system,especially in the assessment of non-elderly patients.
