The clinical effect of low molecular heparin calcium on early onset severe pre-eclampsia
10.3760/cma.j.issn.1008-6315.2012.02.013
- VernacularTitle:低分子肝素钙治疗早发型重度子痫前期临床疗效观察
- Author:
Chongxin TONG
;
Shuwei HAO
;
Xiaofen XING
;
Shuhua QIAO
;
Lin LIU
;
Zhanping DING
- Publication Type:Journal Article
- Keywords:
Early onset severe pre-eclampsia;
Low molecular heparin calcium;
Extended gestational age;
Perinatals
- From:
Clinical Medicine of China
2012;28(2):146-148
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the clinical effects of low molecular heparin calcium on early onset severe pre-eclampsia.Methods Sixty patients with early onset severe pre-eclampsia at 26-34 weeks of gestational age were divided into treatment group(28 cases)and control group(32 cases).The conventional treatment was delivered in control group and low molecalar heparin calcium(LMWHC)was used in treatment group additionally.The time of prolonged gestational age,umbilical arterial S/D ratio,amniotic fluid index,placenta weight,neonatal weight and Apgar score were measured in two groups.Results The time of prolonged gestational age was 10.19 ±4.57days in treatment group and 6.14 ±3.56 days in control group,which were significantly different(P ＜ 0.01).Umbilical arterial S/D ratio,amniotic fluid index,placenta weight and neonatal weight were all significantly different between the two groups(P ＜ 0.05).Neonatal Apgar score in treatment group was remarkably improved(P ＜ 0.01).Conclusion LMWHC treatment in the patients with early onset severe pre-eclampsia could extend gestational age,increase neonatal weight and improve perinatal outcomes.
