Surgical treatment of congenital heart disease combined with severe pulmonary hypertension
10.3760/cma.j.issn.1673-4904.2012.02.003
- VernacularTitle:先天性心脏病合并重度肺动脉高压的外科治疗
- Author:
Kaihu SHI
;
Wei CAO
;
Shengsong XU
;
Wenhui GONG
;
Haiyang XUAN
;
Junxu WU
;
Xudong ZHAO
- Publication Type:Journal Article
- Keywords:
Heart disease;
Hypertension,pulmonary;
Surgical treatment
- From:
Chinese Journal of Postgraduates of Medicine
2012;35(2):7-9
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo explore the surgical treatment of congenital heart disease combined with severe pulmonary hypertension.MethodsThirty-two patients of congenital heart disease combined with severe pulmonary hypertension were included in the study.The saturation of arterial oxygen ranged from 0.84 to 0.94 and echocardiography showed left to right slow velocity shunt in 20 eases,double direction shunt in 10 cases and no shunt in 2 cases.The pulmonary arterial pressure was 65-120 (82 ± 14) mm Hg ( 1 mm Hg =0.133 kPa).All patients received surgical repairs under cardiopulmonary bypass and were treated preoperatively with oxygen inhalation therapy,oral intake of beraprost sodium or silaenafil respectively according to the degree of pulmonary hypertension.During cardiopulmonary bypass,pulmonary artery perfusion was performed with protective solution containing ulinastatin for lung protection.Vasoactive drugs were routinely administrated postoperatively.Results Thirty-two cases underwent the surgical treatment successfully with their postoperative pulmonary arterial pressure decreased 20 -40 mm Hg and 2 cases died of severe low cardiac output syndrome and fatal arrhythmia.The mortality was 6.25％(2/32).ConclusionComprehensive perioperative management followed by radical operation can achieve a good clinical result on congenital heart disease combined with pulmonary hypertension.
