Gastrointestinal mucin genes
10.3760/cma.j.issn.1673-4408.2012.01.004
- VernacularTitle:消化道黏蛋白基因研究进展
- Author:
Yunyun XIE
- Publication Type:Journal Article
- Keywords:
Mucin;
Gastrointestinal diseases
- From:
International Journal of Pediatrics
2012;39(1):11-15
- CountryChina
- Language:Chinese
-
Abstract:
The incidence of gastrointestinal diseases increases every year.Etiology and pathogenesis of gastrointestinal diseases have been not yet elucidated,such as inflammatory bowel disease,gastrointestinal cancers,and allergic diseases.In recent years,the role of mucin genes expression in gastrointestinal diseases has been paying much attention to.Studies have shown that mucins are the main component of mucus in the digestive tract,and a major factor in the formation of the gastrointestinal barrier.Mucins are related to gastrointestinal epithelium,intestinal microflora and inflammatory factors.Abnormal expression of gastrointestinal mucin genes,especially MUC1 and MUC2,are related to Gastrointestinal inflammation and cancer.Currently gastrointestinal mucin genes expression contribute to exploring the diagnosis,treatment and prognosis of digestive diseases.This study is to summarize the progress in gastrointestinal mucin genes expression.
