The application and mechanisms of probiotics in allergic diseases
10.3760/cma.j.issn.1673-4408.2012.01.021
- VernacularTitle:益生菌在过敏性疾病中的应用及作用机制
- Author:
Guina WANG
- Publication Type:Journal Article
- Keywords:
Probiotics;
IgE;
T cell;
Dendritic cell;
Allergic diseases
- From:
International Journal of Pediatrics
2012;39(1):71-74
- CountryChina
- Language:Chinese
-
Abstract:
Probiotics stimulate dendritic cells exert regulatory functions by promoting the release of cytokines,which change the balance of Th1/Th2.This process mediates Th1 cell response instead of Th2 to enhance immune function.Probiotics have shown preventive and therapeutic potential for diseases,including several IgE-related diseases,such as atopic dermattis,asthma and allergic rhinitis.However,because of complex causes and numerous incentives,there is no consistent conclusion regarding probiotics application in allergic diseases.Further evidence-based medical researches will be required in the future.