Effect of Bi-level positive airway pressure ventilation on the hemodynamics in patients with the chronic obstructive pulmonary disease combined coronary heart disease
10.3760/cma.j.issn.1008-6315.2012.010
- VernacularTitle:无创正压通气对慢性阻塞性肺疾病合并冠心病患者血流动力学的影响
- Author:
Kun YANG
;
Lei SUN
;
Li DONG
;
Yanmin JIANG
;
Chunyang GUO
- Publication Type:Journal Article
- Keywords:
Chronic obstructive pulmonary disease;
Bi-level positive airway pressure;
Coronary heart disease;
Hemodynamics
- From:
Clinical Medicine of China
2012;28(1):26-28
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effect of Bi-level positive airway pressure (BiPAP) on hemodynamics in patients with the chronic obstructive pulmonary disease (COPD) combined coronary heart disease.Methods One hundred patients with COPD combined coronary heart disease treated by BiPAP ventilation were enrolled.The blood gas analysis and the hemodynamics were monitored and analyzed in patients with the COPD combined coronary heart disease before treatment and after BiPAP ventilation treatment for 2 hours,24 hours,72 hours and 1 week.Results PaCO2 decreased significantly after 2-hour's treatment by BiPAP ventilation( P ＜ 0.05) and the heart rate and systolic blood pressure also decreased significantly after 24-hour's treatment by BiPAP ventilation.The left ventricurlar ejection fraction( [ 65.63 ± 6.86 ] ％ vs.[ 56.21 ±5.26]％,P ＜ 0.05 )was significantly improved after BiPAP reatilation treatment for one week.The mean pulmonary arterial pressure ( [ 3.74 ± 0.96 ] vs [ 5.12 ± 1.12 ] kPa,P ＜ 0.01 ),angina pectoris ( [ 0.20 ± 0.01 ]time/d vs [ 0.69 ± 0.03 ] time/d,P ＜ 0.05 ) were significantly decreased.Conclusion COPD combined coronary heart disease patients may achieve an optimal effect by BiPAP ventilation.BiPAP ventilation has no impact on the hemodynamics in patients with the COPD combined coronary heart disease.
