Analysis on vision changes and related factors of transnasal transsphenoidal pituitary adenoma resection
10.3760/cma.j.issn.1008-6315.2012.025
- VernacularTitle:经鼻蝶人路垂体腺瘤切除术对视力的影响及相关因素分析
- Author:
Mingxu GE
;
Dawei KONG
;
Hongtao TENG
;
Hongjie WANG
;
Ping SUN
- Publication Type:Journal Article
- Keywords:
Pituitary adenoma;
Vision;
Transnasal transsphenoidal
- From:
Clinical Medicine of China
2012;28(1):64-67
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the factors affecting the vision recovery after transnasal transsphenoidal pituitary adenoma resection.Methods The vision of the left eyes and the right eyes were compared respectively.The vision after and before the operation was also compared by using paired t-test,related factors were analyzed by multiple variable logistic regression model.ResultsThe paired t-test indicated that both eyes' visions were improved after transnasal transsphenoidal pituitary adenoma resection( P ＜0.01 ).The tumor diameter and the vision before operation were two factors affecting the post-operative visions by cumulative logistic regression model.The larger the diameters of the tumors were,the better the vision recoveries after operation( Wald x2 =0.047,OR =2.240,P =0.047).Worse vision lose before operation came up with a better recovery after operation ( Wald x2 =9.684,OR =0.010,P =0.001 ) ; however,age,gender,pathological category,the extent of tumor removal and the time of the vision loss have no significant affects on the vision recovery after operation.ConclusionThe transnasal transsphenoidal pituitary adenoma resection can improve the vision of the patients,and the degree which would to be improved is correlated with the tumor diameter and the vision lose before operation.
