Application of low central venous pressure in liver resection
10.3760/cma.j.issn.1008-6315.2012.028
- VernacularTitle:低中心静脉压在肝切除术中的应用
- Author:
Qidong LI
;
Wei ZHOU
;
Zhengeng JIA
- Publication Type:Journal Article
- Keywords:
Hepatic resection;
Central venous pressure;
Liver cancer
- From:
Clinical Medicine of China
2012;28(1):72-74
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo investigate the feasibility and effectiveness of low central venous pressure (LCVP) in the operation of major hepatic resection.MethodsFourty-eight patients underwent major hepatic resection were randomized into two groups: LCVP and control group.In the LCVP group,CVP was maintained ≤5 cm H2O during the hepatic resection and then returned to normal after resection.In the control group,CVP was maintained normal between 6 -12 cm H20.The duration of hepatectomy,volume of blood loss,volume of blood transfused and renal function were compared between the two groups.ResultsFor the LCVP and control group,the time for hepatectomy was (45 ± 8 ) and ( 35 ± 5 ) min,respectively; the volumes of blood loss were ( 850 ± 160) and (436 ±280)ml,respectively; the blood loss during operation was (490 ± 130) and (270 ± 105 ) ml respectively.The differences were statistically significant (t values were 15.53,7.69 and 17.89 separately,P ＜0.05 ).No significant difference in the renal function was observed before and after the operation ( P ＞ 0.05 ).Conclusion Using LCVP technique during liver resection significantly reduced the operation time,blood loss and blood infusion.And there wa.s no obvious adverse effect on renal function.
