Risk factors and association between cardio-ankle vascular index and carotid atherosclerosis in the patients with type 2 diabetes mellitus
10.3760/cma.j.issn.1008-6315.2012.011
- VernacularTitle:糖尿病患者心踝血管指数与颈动脉硬化的相关性及其危险因素分析
- Author:
Guoxiang TIAN
;
Ling ZHANG
;
Wei ZHANG
;
Wanlin WEI
- Publication Type:Journal Article
- Keywords:
Cardio-ankle vascular index;
Diabetes mellitus;
Carotid intima-media thickness;
Arteriosclerosis;
Risk factors
- From:
Clinical Medicine of China
2012;28(1):28-31
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo study the association between cardio-ankle vascular index (CAVI) and carotid atherosclerosis as well as the risk factors in patients with type 2 diabetes mellitus.MethodsSixty type2 diabetic patients and 60 non-diabetic patients at the same hospitalization period were selected.The clinical features,laboratory test results such as free blood glucose ( FBG),blood lipids and other biochemical markers were recorded.Carotid intima-media thickness (IMT) and CAVI were measured.The relationship between CAVI and carotid atherosclerosis were analyzed; a multivariate linear regression analysis was performed between CAVI and risk factors of type 2 diabetes mellitus.ResultsThe body mass index,triglycerides,FBG,HbA1 c,IMT,the incidence of carotid artery plaque and CAVI values of diabetic group were significantly higher than that of nondiabetic group.Difference between the two groups was statistically significant ( all P ＜ 0.05 ) ; CAVI and carotid IMT was significantly correlated to each other( r =0.435,P ＜ 0.01 ) ; Multiple linear regression analysis showed that CAVI was significantly correlated to age (β =0.458,P ＜0.01 ),triglycerides (β =0.058,P =0.012),FBG (β =0.168,P =0.002) and HbAlc (β =0.228,P =0.003).ConclusionCAVI inpatients with diabetes was positively correlated with carotid IMT.Age,diabetes,triglycerides,FBG and HbAlc are independent risk factors for arterial stiffness.
