Comparison between the MR diffusion weighted imaging and pathology of hepatic alveolar echinococcosis
10.3760/cma.j.issn.1005-1201.2012.01.014
- VernacularTitle:MR扩散加权成像的肝泡状棘球蚴边缘带影像特征与组织病理学对照分析
- Author:
Bo REN
;
Jing WANG
;
Wenya LIU
;
Hao WEN
;
Wei ZHANG
;
Hu XIAO
- Publication Type:Journal Article
- Keywords:
Echinococcosis,hepatic;
Magnetic resonance imaging;
Comparative study
- From:
Chinese Journal of Radiology
2012;46(1):57-60
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the value of DWI and ADC in evaluation the pathologic characteristics of hepatic alveolar echinococcosis (HAE).Methods Twenty six patients with HAE underwent routine MRI and DWI ( b =500,800 s/mm2 ) scan,ADC values of different part including the center,peripheral area and surrounding zone of the lesion were measured,respectively.One-way ANOVA was used for comparing the ADC values of two groups.HE staining specimens and MVD of peripheral area of the lesion were analyzed by different pathological staining methods.The correlation between MVD and ADC values of the peripheral area was analyzed by using the Pearson rank correlation analysis.ResultsTotally 32 lesions were detected in 26 HAE patients.The ADC values of the center,the peripheral zone and the surrounding area of the lesions were (1.3 ±0.3) × 10-3,(1.1 ±0.4) × 10-3 and (1.8 ±0.5) ×10 -3 mm2/s when b =500 s/mm2,but when b =800 s/mm2,the ADC values were ( 1.2 ± 0.4) × 10 -3,(1.1 ± 0.3) × 10-3 and (1.9 ± 0.4) × 10-3 mm2/s,respectively.There were significant difference of the ADC values between two groups(P ＜0.01 ).The significant differences of the ADC values were also found in different area of the lesion (P ＜ 0.05 ).There were no correlation was found between ADC value and MVD [(12.9 ± 3.7)/HP] in the peripheral area of HAE(r =-0.042 and -0.077,P ＞ 0.05).ConclusionsDWI reflected the heteromorphism of peripheral zone and help to identify the infiltration area and biological boundary.No relationship was found between the ADC values of peripheral zone of lesion and MVD.
