Pancreas transplantation for diabetes mellitus
10.3760/cma.j.issn.1000-6699.2012.01.025
- VernacularTitle:胰腺移植治疗糖尿病
- Author:
Haoming TIAN
;
Huaiqing CHEN
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus;
Pancreas transplantation;
Islet transplantation;
Insulin-producing cells replacement therapy;
Artificial pancreas
- From:
Chinese Journal of Endocrinology and Metabolism
2012;28(1):85-88
- CountryChina
- Language:Chinese
-
Abstract:
Diabetes mellitus impacts patient survival and quality of life mainly due to its acute and chronic complications.Pancreas transplantation may restore normoglycemia and reduce the complication of insulin-dependent diabetes,thus improving the quality of life and prolonging patient's survival.Although pancreas transplantation requires major surgery and life-long immunosuppression therapy,it currently remains the gold stand for patients with type 1 diabetes mellitus,who do not respond to conventional therapy.Meanwhile,potential of the islet transplantation,insulin-producing cells replacement therapy,and artificial pancreas as the alternative to pancreas transplantation are under investigation.
