Surgical therapy for malignancy patients complicated with hyperthyroidism

VernacularTitle:恶性肿瘤合并甲状腺功能亢进的临床分析
Author: Yang SHAO ; Xianghui HE ; Liwei ZHU
Publication Type:Journal Article
Keywords: Hyperthyroidism; Neoplasms; Intraoperative period; Antineoplastic combined chemotherapy protocols
From: Chinese Journal of General Surgery 2012;27(1):21-24
CountryChina
Language:Chinese
Abstract: Objective To summarize the therapeutic experience on malignancy patients complicated with hyperthyroidism.Methods Clinical date of 10 cases of surgical malignancy complicated with hyperthyroidism admitted from May 2004 to May 2010 in Tianjin Medical University General Hospital were analyzed retrospectively.Results Four cases were treated by subtotal thyroidectomy before radical operation for cancer.Radical operation for cancer was performed on 6 patients after clinical symptoms of hyperthyroidism were controlled by perioperative antithyroid agents.Postoperatively 3 patients complicated with clinical manifestations similar to thyroid crisis.There was no postoperative mortality.Chemotherapy was given to 10 patients,and 1 patient was discontinued for chemotherapy caused leucopenia.Conclusions Hyperthyroidism should be controlled by surgery or antithyroid agents before patients of malignant diseases could proceed with radical surgery.Proper preoperative medication and effective postoperative management can reduce operation risk and help the patients get through the perioperative period safely.