Effects of low-glycemic index meal replacement on management of patients with type 2 diabetes mellitus
10.3760/cma.j.issn.1000-6699.2012.01.014
- VernacularTitle:低血糖指数膳食替代对2型糖尿病患者的防治作用
- Author:
Min CHEN
;
Yanqiu CHEN
;
Li HUA
;
Min ZONG
;
Fei XIAO
;
Qing YI
;
Hua XIE
;
Wei SUN
;
Aifang CHEN
;
Qianru TANG
;
Jingjing JIANG
;
Yifan LIN
;
Danfeng XU
;
Jianqin SUN
- Publication Type:Journal Article
- Keywords:
Low glycemic index;
Meal replacement;
Diabetes mellitus,type 2;
Blood glucose control;
Oxidative stress
- From:
Chinese Journal of Endocrinology and Metabolism
2012;28(1):45-47
- CountryChina
- Language:Chinese
-
Abstract:
A total of 127 type 2 diabetic patients were divided into low glycemic index meal replacements (intervention) group and standard food-based diet (reference) group in an experiment for 12 weeks.The results showed that fasting plasma glucose,postprandial 2 h plasma glucose,fasting insulin,and homeostasis model assessment insulin resistance(HOMA-IR) in the intervention group decreased significantly after 12 weeks trial ( P＜0.05 or P＜0.01 ).However,there were no significant changes in lipid profile and HbA1C in intervention group.In addition,percentage of body fatty,visceral fatty area,and waist-hip ratio also decreased in intervention group( all P＜0.01 ).Superoxide dismutase and glutathione levels increased significantly in intervention group by the end of trial (both P＜0.01 ),while malondialdehyde was decreased (P＜0.01 ).There were no significant changes in the aforementioned indices in the reference group.Weight,body mass index,and waist circumferences were decreased in both groups,but without significant difference between the two groups.
