Catheter-directed thrombolysis for patients with acute deep venous thrombosis of the lower limb: report of 32 cases
10.3760/cma.j.issn.1007-631X.2012.01.011
- VernacularTitle:介入导管溶栓治疗急性下肢深静脉血栓形成32例
- Author:
Guiyun XU
;
Houwen JIANG
;
Lijun HAO
;
Chuang CHEN
- Publication Type:Journal Article
- Keywords:
Venous thrombosis;
Anticoagulants;
Catheter ablation;
Popliteal vein;
Vena cava filters
- From:
Chinese Journal of General Surgery
2012;27(1):28-30
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate catheter-directed thrombolysis via the popliteal vein in the treatment of the lower limb acute deep venous thrombosis.Methods From July 2009 to October 2010,32patients of the lower limb acute deep venous thrombosis including 3 patients with concurrent pulmonary embolism underwent uhrasound-guided catheter-directed thrombolysis via the popliteal vein.The thrombolytic catheter was inserted into thrombus,through which urokinase was infused at a dosage of 100 × 104U/d.The venous patency score and the rate of patency improvement were observed by venograms before and after therapy.Results In every patient,the lower limb swell and pulomonary symptoms relieved.The circumferences between affected and normal thigh before and after the thrombolysis were(5.4 ± 1.4)cm and (1.7 ± 1.3)cm(t =9.92,P ＜0.01).The circumferences between affected and normal leg before and after the thrombolysis were(4.1 ± 1.5)cm and(1.5 ±0.7)cm(t =7.65,P ＜0.01).The venous patency score before and after the thrombolysis were(15 ± 4)and(4 ± 3)(t =7.12,P ＜ 0.01).The mean rate of venous patency was 88.21％.In the 3 patients with pulmonary embolism,thrombus was complete dissolved in 1 case and partial dissolved in 2 cases.No major complications occurred in all these patients.29 patients were followed up for 3-12 months.There were no thrombosis relapsed.Conclusions Catheter-directed thrombolysis via the popliteal vein with urokinase for acute lower limb deep venous thrombosis is safe and effective.
