Tumor necrosis factor-related apoptosis-inducing ligand and its roles in cerebral ischemia
10.3760/cma.j.issn.1673-4165.2011.12.013
- VernacularTitle:肿瘤坏死因子相关凋亡诱导配体及其在脑缺血中的作用
- Author:
Yang XU
;
Xuelian ZHAO
;
Xuesong WU
;
Zhaohu CHU
- Publication Type:Journal Article
- Keywords:
TNF-related apoptosis-inducing ligand;
Receptors,TNF-related apoptosisinducing ligand;
Brain ischemia;
Atherosclerosis;
Apoptosis
- From:
International Journal of Cerebrovascular Diseases
2011;19(12):940-943
- CountryChina
- Language:Chinese
-
Abstract:
Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) can be induced in ischemia and other pathological states and mediate neuronal apoptosis after cerebral ischemia.Understanding the upregulation mechanism of TRAIL in ischemic brain tissue is promising to develop new treatment for stroke.