Effects of safflower oil on adipose-associated gene expression in mice

VernacularTitle:红花油对肥胖小鼠脂肪组织肥胖相关基因表达的影响
Author: Zhong ZHANG ; Guanyu WANG
Publication Type:Journal Article
Keywords: Safflower oil; Mice; Adipose tissues; Adipose-associated gene
From: Chinese Journal of Endocrinology and Metabolism 2012;28(1):76-78
CountryChina
Language:Chinese
Abstract: Seventy C57BL/6 mice were divided into control group,lard group,lard transferred into safflower oil group,and safflower oil group.After 20 weeks,the white adipose tissues were taken to analyse the gene differentiational expression prolife.The results showed that body weight,blood glucose and lipids,and insulin levels in lard group were higher than those in control group( all P＜0.05 ),which were decreased after lard was transferred into safflower oil for 10 weeks( all P＜0.05 ).Safflower oil regulated some of the orexigenic genes,anorectic genes,and the genes involved in energy expenditure in adipose tissues such as opioid receptor,glucagon,and PPARα.