Mechanisns of bone marrow stromal cells in the treatment of ischemic stroke
10.3760/cma.j.issn.1673-4165.2011.12.012
- VernacularTitle:骨髓基质细胞治疗缺血性卒中的机制
- Author:
Fangqin LI
;
Lei ZHU
;
Jing WANG
;
Yujun PAN
- Publication Type:Journal Article
- Keywords:
Bone marrow cells;
Stromal cells;
Stem cell transplantation;
Stroke;
Brain ischemia
- From:
International Journal of Cerebrovascular Diseases
2011;19(12):935-939
- CountryChina
- Language:Chinese
-
Abstract:
Bone marrow stromal cells are a kind of non-hematopoietic stem cells in the bone marrow.They possess self-renewing capability and multilineage differentiation potential.They are the ideal cell source for cell transplantation in the treatment of various diseases.A large number of animal model experiments shown that BMSC transplantation can promote brain structure and functional recovery after cerebral ischemia through a variety of mechanisms and provide new ideas and methods for the treatment of cerebrovascular diseases.This article reviews the mechanisms of BMSCs in the treatment of ischemic stroke in recent years.
