Metabolic syndrome in liver transplant recipients:prevalence and risk factors
10.3760/cma.j.issn.1007-631X.2012.01.004
- VernacularTitle:肝移植术后代谢综合征及危险因素分析
- Author:
Xinyu LI
;
Jiye ZHU
;
Lei HUANG
;
Guangming LI
;
Xisheng LENG
- Publication Type:Journal Article
- Keywords:
Liver transplantation;
Metabolic syndrome;
Risk factors
- From:
Chinese Journal of General Surgery
2012;27(1):8-11
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the prevalence and risk factors of posttransplantation metabolic syndrome(PTMS)in liver transplant recipients.Methods According to NCEP-ATP Ⅲ(2001)standard,we assessed for the presence of PTMS in 102 transplant recipients which have lived ≥ 5 yesrs after liver transplantation.Age ≥ 50 years,the male sex,history of smoking,preoperative obesity,preoperative hypertension,preoperative diabetes,and preoperative hypertriglyceridemia were selected for evaluation.Predictors for PTMS were tested using Logistic regression analysis.Results Among 102 patients assessed,the prevalence of PTMS was 51.9％ compared with 29.3％ pretransplant level.Obesity(body mass index ＞ 28 kg/m2),hypertriglyceridemia(＞ 1.7 mmol/L),high-density lipoprotein cholesterol ＜ 1.0 mmol/L(men)or ＜ 1.3 mmol/L(women),hypertension,and diabetes were significantly more common in patients after transplantation.The independent factors associated with PTMS were older age,preoperative obesity and preoperative diabetes.Conclusions PTMS is highly prevalent among transplant recipients,older age(＞ 50 years),preoperative obesity and preoperative diabetes are among the risk factors for PTMS.
