Screening and surveillance of hepatocellular carcinoma.
- Author:
Myung Ah LEE
1
Author Information
1. Division of Oncology, Department of Internal Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea.
- Publication Type:Review
- Keywords:
Hepatocellular carcinoma;
Surveillance;
Screening
- MeSH:
alpha-Fetoproteins;
Biomarkers;
Carcinoma, Hepatocellular;
Hepatitis;
Hepatitis B;
Hepatitis, Alcoholic;
Humans;
Korea;
Liver Diseases;
Male;
Mass Screening;
Organothiophosphorus Compounds;
Risk Factors
- From:Korean Journal of Medicine
2010;79(3):224-230
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Hepatocellular carcinoma (HCC) is common cancer in Korea. Although HCC has been decreased recently, mortality rate is still high, especially in the 6th decades in men. While hepatitis B and C viral hepatitis is the most common cause of HCC, alcoholic hepatitis is being the major risk factor in Korea. For early detection of HCC, it is important to identify the risk group and to monitor with regular interval. Serum alpha fetoprotein and abdominal ultrasonography is mainstay for screening of HCC. Recently, new advanced techniques, including new biomarkers have been developed and introduced, but it is not certain for its usefulness as a screening method. The screening program suggested by National Cancer Center and associated society of liver disease is widely used in Korea. Based on screening programs, individual personalized surveillance program is needed for the high risk patients in practice.
