Obstructive sleep apnea as an independent risk factor for stroke: possible mechanislms
10.3760/cma.j.issn.1673-4165.2011.12.007
- VernacularTitle:阻塞性睡眠呼吸暂停作为缺血性卒中独立危险因素的可能机制
- Author:
Zhang SHENG
;
Yin MEI
- Publication Type:Journal Article
- Keywords:
Sleep apnea syndromes;
Stroke;
Brain ischemia;
Atherosclerosis;
Oxidative stress;
Inflammation;
Hemostasis;
Cerebrovascular circulation;
Risk factors
- From:
International Journal of Cerebrovascular Diseases
2011;19(12):911-915
- CountryChina
- Language:Chinese
-
Abstract:
Obstructive sleep apnea (OSA),the most common type of sleep disordered breathing was closely associated with the occurrence of ischemic stroke.It has been demonstrated that OSA is an independent risk factor for ischemic stroke.Its pathogenic mechanism includes atherosclerosis,coagulation abnormalities and cerebral hemodynamic changes caused by long-term periodic hypoxia hypoxemia and hypercapnia.The prognosis of ischemic stroke patients with OSA is poor.Therefore,it needs to be treated early to avoid further damage to brain tissue and reduce the mortality.
