Clinical outcome of the combined nutritional support for colorectal cancer patients at nutritional risk: a retrospective study of 60 cases
10.3760/cma.j.issn.1674-635X.2011.06.001
- VernacularTitle:有营养风险患者术后肠内、肠外营养支持模式与不经筛查术后全部应用肠外营养对结直肠癌患者结局的影响:60例回顾性研究
- Author:
Danian TANG
;
Mingwei ZHU
;
Jianhua SUN
;
Qi AN
;
Hongyuan CUI
;
Jifang MEN
;
Junmin WEI
- Publication Type:Journal Article
- Keywords:
Colorectal cancer;
Nutrition risk screening;
Nutrition support;
Clinical outcome
- From:
Chinese Journal of Clinical Nutrition
2011;19(6):355-359
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo explore the clinical outcome of the combined nutrition support for colorectal cancer patients.MethodsTwo research arms were obtained using a cohort sampling method.Ann A ( the study group): from 2009 to 2010,30 colorectal cancer patients were enrolled.They received nutritional risk screening (NRS) 2002 after admission.Nutritional risk was defined as NRS 2002 score ≥3 three days before operation.Patients with nutritional risk received enteral nutrition (EN) for bowel preparation without laxative drug and enema.After operation,they received EN combined with parenteral nutrition (PN) supports provided.Arm B (control group): 30 cases with historically confirmed colorectal cancer were enrolled from 2007 to 2008.They received routine bowel preparation (diet control,laxative drug,and enema) and PN supports after operation.Nutritional parameters,the rate of infectious complications,the rate of systemic inflammatory response syndrome,and the duration of hospital stay were analyzed.ResultsThere were no significant difference in body weight and plasma albumin between these two arms ( P ＞ 0.05 ). The incidence of systemic inflammatory response syndrome (13.3 ％ ),infectious complications (10.0％ ),and the duration of hospital stay [ (12.3 ± 6.5 ) d ] in arm A were significantly lowerthan those in arm B [33％,30％,and (15.0 ±7.2) d,respectively] (P =0.038,P =0.042,P =0.045).Conclusion For the colorectal cancer patients,nutritional risk screening on admission,bowel preparation with eneral nutrition before operation,and combined nutritional support after operation can improve the clinical outcome.
