Effect of oral tramadol controlled release tablets premedication on efficacy of anesthesia with target-controlled infusion of propofol and remifentanil for painless colonoscopy in elderly patients
10.3760/cma.j.issn.0254-1416.2011.10.010
- VernacularTitle:术前口服曲马多缓释片对老年患者无痛肠镜诊疗术中靶控输注异丙酚复合瑞芬太尼麻醉效果的影响
- Author:
Yu ZHANG
;
Lubo GAO
;
Jincheng LI
- Publication Type:Journal Article
- Keywords:
Tramadol;
Propofol;
Piperidines;
Drug delivery systems
- From:
Chinese Journal of Anesthesiology
2011;31(10):1200-1202
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effect of oral tramadol controlled release tablets premedication on the efficacy of anesthesia with target-controlled infusion (TCI)of propofol and remifentanil for painless colonoscopy in elderly patients.Methods Sixty ASA Ⅰ or Ⅱ patients,aged≥ 65 yr,undergoing painless colonoscopy,were randomly divided into 2 groups ( n =30 each): control group (group C) and tramadol group(group T).In group T tramadol controlled-release tablet 100 mg was administered orally at 2 h before operation.Anesthesia was induced and maintained with TCI of propofol and remifentanil.SP,DP,HR and SpO2 were recorded before induction,at the time to reach the ileocecal valve and at the end of operation.The induction time,duration of operation,emergence time,recovery time,adverse events and the amount of propofol and remifentanil consumed were recorded.Results There was no significant difference in hemodynamics parameters,induction time,duration of operation,emergence time,recovery time,adverse events and the amount of propofol and remifentanil consumed between the two groups (P ＞ 0.05 ).Conclusion Oral tramadol controlled release tablets 100 mg premedication can be safely used in painless colonoscopy in elderly patients,however,tramadol can not enhance the efficacy of anesthesia with TCI of propofol and remifentanil.
