Advancement in stimuli-sensitive drug delivery system
10.3760/cma.j.issn.1673-4181.2011.06.011
- VernacularTitle:刺激反应性释药系统的研究进展
- Author:
Gui WU
;
Qixin ZHENG
- Publication Type:Journal Article
- Keywords:
Intelligent;
Hydrogel;
Magnetic nanoparticle;
Drug delivery system
- From:
International Journal of Biomedical Engineering
2011;34(6):367-370
- CountryChina
- Language:Chinese
-
Abstract:
Stimuli-sensitive drug delivery system (SSDDS) is an novel drug delivery carrier.It is sensitive to either the internal physiopathologic changes (pH,temperature) of the body or external stimulus signal (ultrasound,magnetic signal) and controls the release of the drugs that it carries according to the variation of physicochemical property which stimulated by the signals.SSDDS can be prepared from hydrogels,liposomes and magnetic nanoparticles.In contrast to non-stimuli-responsive drug delivery system,SSDDS has remarkable advantages including feedback regulation,stronger controllability and targeting therapy.This paper will review the advancement in stimuli-responsive drug delivery system in recent years.
