The syndrome of inappropriate antidiuretic hormone secretion: the level on its diagnosis and treatment should be improved
10.3760/cma.j.issn.1000-6699.2011.11.001
- VernacularTitle:提高抗利尿激素分泌异常综合征的诊治水平
- Author:
Xiaohui GUO
;
Aimei DONG
- Publication Type:Journal Article
- Keywords:
Syndrome of inappropriate antidiuretic hormone secretion;
Hyponatremia;
Vasopressin receptor antagonist
- From:
Chinese Journal of Endocrinology and Metabolism
2011;27(11):873-875
- CountryChina
- Language:Chinese
-
Abstract:
The syndrome of inappropriate antidiuretic hormone secretion ( SIADH ),characterized with dilutional hyponatremia,is the most frequent pathophysiology of euvolemic hyponatremia in hospital inpatients.Conventional therapies for SIADH include fluid resriction,saline infusion,and some pharmacologic adjustments of fluid balance.For various reasons,conventional therapies show poor efficiency.Vasopressin receptor antagonist,a new class of pharmacologic agent,can directly block vasopressin-mediated receptor activation and target underlying pathophysiology of SIADH.
