The effect of living donor right liver wafting with middle hepatic vein on early remnant liver congestion and regeneration of the donors
10.3760/cma.j.issn.1007-631X.2011.10.003
- VernacularTitle:切取肝中静脉对活体肝移植供者早期残肝淤血和再生的影响
- Author:
Qingjun GUO
;
Wentao JIANG
;
Honghai WANG
;
Yonglin DENG
;
Zhijun ZHU
;
Cheng PAN
;
Hong ZHENG
;
Zhongyang SHEN
- Publication Type:Journal Article
- Keywords:
Living donor;
Liver transplantation;
Congestion;
Regeneration
- From:
Chinese Journal of General Surgery
2011;26(10):807-810
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo investigate the effect of living donor right liver graft transplantation (LDLT) with middle hepatic vein (MHV) on the early congestion and regeneration of the donor remnant liver.MethodsBetween August 2008 and August 2009,28 LDLT were performed with 11 LDLT without MHV (group A) and 17 LDLT with MHV (group B).The donor operative time,intraoperative blood loss,postoperative hospital stay,bilirubin,INR,and ALT level were recorded in detail.We measured the volume of remnant liver by means of CT scan 2 weeks after operation and compare the degree of congestion and regeneration of the remnant liver between the two groups.ResultsThere were 10 cases in group B and 0 cases in group A suffering from congestion at segment Ⅳ,and the difference was significant(P =0.006).In group B,6 cases in type Ⅰ and 4 cases in type Ⅱ developed congestion at segment Ⅳ,and the difference was significant(P=0.035).Two weeks post operation,the volume of segment Ⅳ in group B was smaller than in group A(P=0.005).The regeneration rate of segment Ⅳ in group B was smaller than in group A (P =0.007),on the contrary,the regeneration rate of segment Ⅰ - Ⅲ in group B was larger than in group A( P =0.008 ).But the regeneration rate of remnant liver was the same in both groups (P =0.63 ).ConclusionsThe right lobe hemihepatectomy with MHV does not damage the early liver function of the donor significantly.The segment Ⅳ of the remnant liver suffered from congestion and impeded the regeneration,but was compensated by the regeneration of segments Ⅰ - Ⅲ.
