De novo malignancies after liver transplantation
10.3760/cma.j.issn.1007-631X.2011.10.005
- VernacularTitle:肝移植术后新发恶性肿瘤的治疗
- Author:
Pengji GAO
;
Xisheng LENG
;
Guangming LI
;
Jiye ZHU
- Publication Type:Journal Article
- Keywords:
Liver transplantation;
Neoplasms recurrence,local;
De novo malignancy;
Burkittlymphoma
- From:
Chinese Journal of General Surgery
2011;26(10):814-816
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo investigate the incidence of de novo malignancies in liver transplantation recipients.MethodsWe retrospectively assessed data of 475 patients undergoing liver transplantation from May 2000 to December 2008. ResultsAmong the 475 recipients followed-up for 6 months at minimum,5 patients developed de novo malignancy and the total incidence rate was 1.1％.The median elapsed time from transplant to the diagnosis of de novo malignancy was 14 months (range 6 to 72).The patients were all males,including one of rectal cancer which was cured by radical resection,2 of hepatocellular carcinoma who died 6 and 14 months respectively after the diagnosis,1 of neuroendocrine carcinoma of the lung dying after 16 months,1 of Bukitt lymphoma who died within 2 months.Conclusions De novo malignancy is an uncommon event in liver transplantation recipients,but the outome is very poor.
