Relationship between iodine intake and the prevalence of thyroid disease in Urumqi, Xinjiang
10.3760/cma.j.issn.1000-6699.2011.12.003
- VernacularTitle:新疆乌鲁木齐地区人群碘摄人量与甲状腺疾病的相关研究
- Author:
Mingchen ZHANG
;
Li ZHANG
;
Yong FAN
;
Xiaoyun ZENG
;
Yun ZHU
- Publication Type:Journal Article
- Keywords:
Idoine;
Thyroid function;
Thyroid nodule
- From:
Chinese Journal of Endocrinology and Metabolism
2011;27(12):972-974
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the relationship between iodine intake and the prevalence of thyroid diseases in Urumqi.Methods A total of 1693 subjects were investigated.Serum thyroid hormones,thyroid autoantibodies,and urinary iodine concentration were determined,and type B ultrasonography of thyroid gland was performed in all participants.Result The urinary iodine level revealed that 9.5% of the subjects were iodine deficient and 30.0% iodine excessive.The average median urinary iodine was 254.9 μg/L.Serum total T4 level in the idione adequate and more than adequate groups was significantly higher than the other 2 groups [ ( 9.02±2.63 ) vs (7.69±2.85)、(8.45 ±2.13 ) μg/dl,both P<0.05 ],and serum TSH level in the idione deficient group was significantly higher than the other 2 groups [ (3.00±1.86) vs (2.37±1.91),(2.27±1.86) mIU/L,both P<0.01 ].There was no significant statistical difference in positive rates of thyroid autoantibodies,morbidities of thyroid dysfunction and goiter among 3 groups.Conclusion The iodine deficient situation has been corrected in Urumqi.There is no difference in morbidities of thyroid diseases in population with different iodine intakes.