Endovascular treatment for severe Takayasu's arteritis
10.3760/cma.j.issn.1007-631X.2011.10.014
- VernacularTitle:重症头臂型大动脉炎的血管腔内治疗
- Author:
Hong JIANG
;
Jun QIAN
;
Hao YAN
;
Peiyan DUAN
;
Lin QIAO
;
Hui CHEN
;
Guangchao YU
- Publication Type:Journal Article
- Keywords:
Arteritis;
Ischemic attack,transient;
Angioplasty,balloon;
Stents;
Restenosis
- From:
Chinese Journal of General Surgery
2011;26(10):841-844
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo evaluate the clinical application of endovascular treatment for severe Takayasu's arteritis (TA).MethodsIn this study,35 target lesions in 32 patients [28 women,mean age (30 ±8) years] with severe Takayasu's arteritis were treated with endovascular merthod.The average length of lesion was 3.1 cm( range 2.7 -5.3).The overall average degree of diameter stenosis was 90％ ± 11％ (range 70- 100)in which 15 lesions were completely occlusive.There were 10 patients whose ESR were higher than 20 mm/h( range 25 -37).Follow-up included physical examination and patency evaluated by color duplex souography/computed tomography angiography/angiography at 6 months and then annually.ResultsRecanalization was unsuccessful in 3 completely occlusive lesions,with a successful rate of 80％(12/15).There was one case in which embolization leading to acute thrombogenesis developed during interventional procedure and resulting in severe stroke.The technical successful rate ( residual stenosis ＜ 50％ ) was 88.6％ ( 31/35 ).The transient cerebral ischemia attack ( TIA ) symptoms disappeared in 31 cases.26 cases were followed up for an average of (19 ± 10) months (range 13 -40).Occipital infarction following severe in-stent restenosis developed 13 months later in one case.Symptomatic in-stent restenosis18monthslaterwasfoundin2cases. Patencyratewas88.5％( 23/26 ).ConclusionsEndovascular treatment is safe and effective for severe TA.Strict indication and accurate targeting the lesions help ensure the success of management.
