Liver transplantation from donation after cardiac death (report of 3 cases)
10.3760/cma.j.issn.0254-1785.2011.12.003
- VernacularTitle:心脏死亡供者供肝移植三例报告
- Author:
Shurong LIU
;
Gang WU
;
Donghua CHENG
;
Yiman MENG
;
Guichen LI
;
Lei YANG
;
Hong LI
;
Baifeng LI
;
Fengshan WANG
;
Ying CHENG
;
Rui SHI
;
Ying JIN
;
Yongfeng LIU
- Publication Type:Journal Article
- Keywords:
Cardiac death;
Tissue donors;
Liver transplantation
- From:
Chinese Journal of Organ Transplantation
2011;32(12):716-718
- CountryChina
- Language:Chinese
-
Abstract:
Objective To summarize our experience in the liver transplantation from the donation after cardiac death (DCD).Methods The livers from three DCD donors (2 cases of brain trauma and 1 case of cerebral hemorrhage) were harvested according to the Guidelines for Donation after Cardiac Death in China.These grafts were orthotopically transplanted into three recipients including 2 cases of decompensative hepatic cirrhosis and 1 case of primary liver cancer.The warm ischemic time ranged from 7.5 to 10 min and the cold ischemic time was 4.5,8.2 and 6.5 h respectively.Postoperative immunosuppressive regimens included prednisone,FK506 and mycophenolate mofetil (MMF).Antibiotics and anticoagulatants were used accordingly.Results All of the 3 recipients obtained normal liver function within 3 weeks since the grafts were implanted without PNF,thrombosis and rejection.No postoperative complications occurred in 3 recipients during the follow-up period of 2 to 9 months with normal liver function.Conclusion The liver transplant from DCD donor showed good results in our center.Chinese group Ⅲ of DCD donor,UW score above the middle level and the short warm ischemic time are three keys ensuring the success of the liver transplant from DCD donors.
