Research progress of dead-in-bed syndrome in type 1 diabetes
10.3760/cma.j.issn.1000-6699.2011.12.018
- VernacularTitle:睡眠中死亡综合征——1型糖尿病猝死研究进展
- Author:
Yifei MO
;
Jian ZHOU
;
Weiping JIA
- Publication Type:Journal Article
- Keywords:
Dead-in bed syndrome;
Diabetes mellitus,type 1;
Sudden death;
Mechanism
- From:
Chinese Journal of Endocrinology and Metabolism
2011;27(12):1032-1035
- CountryChina
- Language:Chinese
-
Abstract:
Dead-in-bed syndrome (DBS) is a rare but devastating sudden death condition that mainly affects young patients with type 1 diabetes.Its mechanism is quite complicated and may involve multiple factors.Acute onset of recurrent and severe nocturnal hypoglycemia,abnormal cardiac repolarization,genetic factors,and obstructive sleep apnea may all contribute to ventricular arrhythmias and even sudden death.The future research plans include elucidating and understanding the underlying mechanisms and triggers for DBS,developing a risk stratification system,using real-time continuous glucose monitoring system to detect severe nocturnal hypoglycemia,and initiating appropriate therapeutic interventions to uhimately prevent the tragedy.
