Serum 1,5-anhydroglucitol in pregnant women with different glucose tolerance status
10.3760/cma.j.issn.1673-4904.2011.36.003
- VernacularTitle:不同糖耐量状态孕妇血清1,5-脱水葡萄糖醇的研究
- Author:
Jiajian CHEN
;
Zhuolian WEN
;
Liang LIANG
- Publication Type:Journal Article
- Keywords:
Pregnant women;
Diabetes,gestational;
1,5-anhydroglucitol
- From:
Chinese Journal of Postgraduates of Medicine
2011;34(36):6-8
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the diagnosing value of serum 1,5-anhydroglucitol(1,5-AG)for gestational diabetes mellitus(GDM)by determining 1,5-AG in pregnant women with different glucose tolerance status.Methods The levels of serum 1,5-AG,fasting plasma glucose(FPG),1 hour plasma glucose(1hPG)and glycosylated hemoglobin(HbA1c)were determined in 30 cases GDM(GDM group),32 cases gestational impair glucose tolerance(GIGT group)and 43 cases gestational normal glucose tolerance (GNGT group).Results The level of serum 1,5-AG in GDM group[(11.69 ± 3.92)mg/L]was obviously lower than that in GIGT group[(20.93 ± 3.43)mg/L]and GNGT group[(27.83 ± 4.03)mg/L](P ＜ 0.01),GIGT group was obviously lower than that in GNGT group(P ＜0.05).The level of serum 1,5-AG had significantly negative correlation with FPG,1hPG and HbA1c respectively(P＜ 0.01).Conclusion The level of serum 1,5-AG has significantly correlation with glucose tolerance,1,5-AG can be used as useful indicator in the diagnosis of GDM.
