Correlation of serum total bile acid levels with liver tissue inflammation grade in chronic liver diseases
10.3760/cma.j.issn.1674-2397.2011.06.007
- VernacularTitle:慢性肝病患者血清总胆汁酸水平与肝组织炎症分级的量化关系研究
- Author:
Xianjun DING
;
Shibo LI
;
Yuncheng LI
;
Zhejuan YANG
;
Shaozuo LI
;
Huasheng LIU
;
Zhiyi LIN
;
Jianrong HUANG
- Publication Type:Journal Article
- Keywords:
Bile acids and salts;
Inflammation;
Chronic liver disease
- From:
Chinese Journal of Clinical Infectious Diseases
2011;04(6):352-354
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the correlation of serum total bile acid (TBA) levels with the inflammation grades of liver tissue in chronic liver diseases.Methods Cyclophorase assay was used to detect the serum TBA levels in 172 patients with various chronic liver diseases,and the inflammation grades of liver tissue were determined by liver biopsy.The correlation between serum TBA levels and the inflammation grades of liver tissue was evaluated using SPSS 12.0 software.Results Serum TBA level was positively correlated with the inflammation grade of liver tissue ( r =0.275,P ＜ 0.01 ).The inflammation grade reached G2 when serum TBA was 20 μmol/L.Conclusion Serum TBA level may be useful for evaluating the inflammation grade of liver tissue in chronic liver diseases.
