Single nucleotide polymorphisms of susceptibility gene in esophageal squamous cell carcinoma
10.3760/cma.j.issn.1673-422X.2011.12.013
- VernacularTitle:食管鳞癌易感基因的单核苷酸多态性
- Author:
Shizhou YANG
;
Zhiqiang LING
;
Weimin MAO
- Publication Type:Journal Article
- Keywords:
Esophageal neoplasms;
Polymorphism,single nucleotide
- From:
Journal of International Oncology
2011;38(12):917-919
- CountryChina
- Language:Chinese
-
Abstract:
Variants of gene loci on susceptibility genes are the major individual susceptibility factors of esophageal squamous cell carcinoma (ESCC) in China.Some of the gene loci participate in the DNA damage and repair,and some are related with cancer suppressor genes,metabolism enzymes,trace elements and smoking.The single nucleotide polymorphisms of these susceptibility genes are closely correlated with the genesis of ESCC.
