Progress of study on the KAI1 gene in gynecological tumor
10.3760/cma.j.issn.1006-9801.2010.增.032
- VernacularTitle:KAI1基因在妇科肿瘤中的研究进展
- Author:
Jingli WANG
- Publication Type:Journal Article
- Keywords:
Genital neoplasms;
female;
KAI1;
Genes;
tumor suppressor
- From:
Cancer Research and Clinic
2010;22(z1):64-66
- CountryChina
- Language:Chinese
-
Abstract:
KAI1 is a recently identified metastasis suppressor gene located at human chromosome 11 p11.2. KAI1 protein is a member of the structurally distinct family of cell surface glycoprotein and belongs to transmembrane 4 protein superfamily. KAI1 expression is down-regulated in many metastatic tumor cells. Down-regulation of KAI1 expression also plays an important role in the genesis and development of gynecological tumor.
