Effect analysis of compound danshen tablets plus alendronate in treatment of women with postmenopausal osteoporosis

VernacularTitle:阿仑磷酸钠联合复方丹参片治疗绝经后骨质疏松症患者的效果评价
Author: Yumei LIANG ; Weibo WU ; Lamei HOU
Publication Type:Journal Article
Keywords: Alendronate; Compound danshen tablets; Postmenopausal women; Osteoporosis
From: Chinese Journal of Practical Nursing 2011;27(18):29-31
CountryChina
Language:Chinese
Abstract: Objective To assess whether treatment with compound danshen tablets plus alendronate would be safe and effective in women with postmenopausal osteoporosis. Methods 180 women with postmenopausal osteoporosis were randomized to receive combination therapy and independent therapy with compound danshen tablets and alendronate for 6 months. Scores of VRS were assessed,mean serum alkaline phosphatase, serum osteocalcin, urinary creatinine, urinary hydroxyproline, urinary calcium were detected. Bone mineral density of lumbar vertebra 1 ~5 was determined by dual X - ray absorptiometry. Results Mean serum alkaline phosphatase, serum osteocalcin, and urinary creatinine, urinary hydroxyproline, urinary calcium were statistically different between the combination therapy group and the independent therapy group, and bone mineral densities increased in all therapy groups while there was higher elevated level in the combination therapy group. Conclusions The combination therapy of compound danshen tablets with alendronate has a favorable influence on women with postmenopausal osteoporosis.