Adjuvant immunotherapy in neonatal sepsis: advances in treatment
10.3760/cma.j.issn.1673-4408.2011.04.005
- VernacularTitle:新生儿败血症的免疫及辅助治疗进展
- Author:
Danfang LU
- Publication Type:Journal Article
- Keywords:
Sepsis;
Immunology system;
Neonatal;
Preterm infant
- From:
International Journal of Pediatrics
2011;38(4):325-328
- CountryChina
- Language:Chinese
-
Abstract:
Systemic infections in newborns cause significant morbidity and mortality in spite of appropriate antimicrobial therapy. Consequently, Immune and adjuvant therapy has emerged as a potential adjuvant therapeutic modality to reduce the morbidity and mortality associated with neonatal sepsis. There were many recent trails including a few of animal trails described the use of intravenous immunoglobulin and colony stimulating factors in neonatal sepsis. In addition, the most recent findings describing the use of probiotics, glutamine supplementation, recombinant human protein C, lactoferrin and pentoxifylline in the treatment of neonatal sepsis have been reviewed.
