S100B and acute ischemic cerebral injury
10.3760/cma.j.issn.1673-4165.2011.06.013
- VernacularTitle:S100B与急性缺血性脑损伤
- Author:
Zhouwei YU
;
Guinan BI
- Publication Type:Journal Article
- Keywords:
S100 proteins;
Brain ischemia;
Stroke;
Biological markers
- From:
International Journal of Cerebrovascular Diseases
2011;19(6):466-470
- CountryChina
- Language:Chinese
-
Abstract:
S100B is a class of acid calcium-binding protein. It mainly exists in neuroglial cells in the central nervous system, and it is one of the signs of astrocyte activation. S100B may reflect the function of neuroglial cells and regulate the complex interactions between the neurons and neuroglial cells. Studies in recent years have demonstrated that S100B protein is involved in the pathological processes of acute ischemic brain injury. Serum S100B protein can be used as an important marker for identifying the severity of cerebral infarction, progress and outcome.
