Clinical progress of measuring tumor cell proliferation with 18F-FLT PET
10.3760/cma.j.issn.1673-422X.2011.07.006
- VernacularTitle:18F-FLT PET显像预测肿瘤增殖的临床研究进展
- Author:
Zhongjie CHEN
;
Jinming YU
- Publication Type:Journal Article
- Keywords:
3′-Deoxy-3′-l8F-fluorothymidine;
Neoplasms;
Cell proliferation
- From:
Journal of International Oncology
2011;38(7):499-502
- CountryChina
- Language:Chinese
-
Abstract:
3′-deoxy-3′-18F-fluorothymidine has been described recently as a new positron emission tomography (PET) tracer for imaging tumor cell proliferation. In recent years, more and more clinical research demonstrate that 18F-FLT can image tumor cell proliferation during treatment, and can reflect accelerated reproliferation earlier. it can define tumor subvolumes with high proliferative activity preceding volumetric tumor response, and can predict relapse and prognosis according to the changing status during the treatment.
