miR-200 family and its mechanism
10.3760/cma.j.issn.1673-422X.2011.07.002
- VernacularTitle:miR-200及其作用机制
- Author:
Juan SU
;
Qingyu ZHANG
- Publication Type:Journal Article
- Keywords:
microRNAs;
Neoplasms;
Epithelial-mesenchymal transition
- From:
Journal of International Oncology
2011;38(7):486-489
- CountryChina
- Language:Chinese
-
Abstract:
MiR-200 family is a cluster of miRNAs closely linked to EMT. The miR-200 family contains miR-200a, miR-200b, miR-200c, miR-141 and miR-429. Many studies have shown that miR-200 family are key regulators of EMT and determine the epithelial phenotype. They are important to both EMT development and tumor progression. This paper reviews the advancement in the research of miR-200 family and its mechanism.
