MicroRNA involvement in metastasis and recurrence of breast Cancer
10.3760/cma.j.issn.1673-4203.2011.07.018
- VernacularTitle:microRNA与乳腺癌转移、复发的关系
- Author:
Dan LIAO
;
Shanshan CHEN
;
Herui YAO
- Publication Type:Journal Article
- Keywords:
micro RN A;
Breast cancer;
Metastasis;
Recurrence
- From:
International Journal of Surgery
2011;38(7):491-495
- CountryChina
- Language:Chinese
-
Abstract:
MicroRNAS( miRNAs) are a class of single strand, small non-coding RNAs about 22 nucleotides, which have the function to regulate gene expression post-transcriptionally and control the biological processes,such as proliferation, differentiation and apoptosis. Recent studies indicate that miRNA plays an important role in tumor involved in invasion and metastasis. This article mainly reviews the feature of miRNA and its effect in metastasis or recurrence of breast cancer.