Mechanism of hepatitis B virus X protein promoting hepatocellular carcinoma metastasis-associated molecules
10.3760/cma.j.issn.1673-422X.2011.06.019
- VernacularTitle:乙肝病毒X蛋白促进肝细胞癌侵袭转移相关分子的作用机制
- Author:
Na LIU
;
Faqing TANG
- Publication Type:Journal Article
- Keywords:
Hepatitis B virus X protein;
Carcinoma,hepatocellular;
Neoplasm metastasis
- From:
Journal of International Oncology
2011;38(6):456-459
- CountryChina
- Language:Chinese
-
Abstract:
Hepatocellular carcinoma(HCC)shows high malignancy and metastasis. Hepatitis B virus X protein (HBx), a virus protein coded by hepatitis B virus, plays an important role in HCC metastasis. Recently, it was reported that HBx activates metastatic signal-pathways through MMPs, VEGF, uPA etc.,and promotes metastasis of hepatocellular carcinoma.
