Salvage liver transplantation for patients with recurrent hepatocellular carcinoma after curative resection
10.3760/cma.j.issn.0254-1785.2011.06.006
- VernacularTitle:挽救性肝移植治疗肝癌切除术后肿瘤复发
- Author:
Xiaoshun HE
;
Linwei WU
;
Zhiyong GUO
;
Xiaofeng ZHU
;
Dongping WANG
;
Weiqiang JU
;
Yi MA
;
Guodong WANG
;
Qiang TAI
;
Anbin HU
- Publication Type:Journal Article
- Keywords:
Liver transplantation;
Liver neoplasms;
Recurrence
- From:
Chinese Journal of Organ Transplantation
2011;32(6):343-346
- CountryChina
- Language:Chinese
-
Abstract:
Objective To summarize the experience with salvage liver transplantation for patients with recurrent hetaptocellular carcinoma(HCC)after primary liver resection.Methods From 2004 to 2008,376 patients with HCC received liver transplantation in our single center.Among these patients,36 (9.6 %)underwent salvage liver transplantation after primary liver curative resection due to intrahepatic recurrence.There were 29 males and 7 females with the mean age of 46 years old.Sixteen received right lobectomy,10 received left lobectomy and the others received sectionectomy or segmentectomy.As a control group for comparison,we used clinical data of the 147 patients who underwent primary OLT for HCC within Milan Criteria.Results The mean interval between initial liver resection and salvage transplantation was 34.9±16.2 months(1-63 months).Intraoperative bleeding volume,transfusion volume and operative time in the salvage group were significantly different from those in control group (P<0.05).There were no significant difference in post-operative complications,tumor recurrence rate,survival rate and tumor-free survival between these two groups(P>0.05).Conclusion In comparison with primary OLT,although salvage liver transplantation would increase the operation difficulties,it still remains a good option for patients with HCC recurrence after curative resection.
