Clinical analysis of primary duodenal adenocarcinoma of 89 cases

VernacularTitle:十二指肠腺癌89例临床分析
Author: Sisen ZHANG ; Lei CHEN ; Xisheng LENG ; Xiefu ZHANG ; Yongfu SHAO
Publication Type:Journal Article
Keywords: Duodenal neoplasms; Adenocarcinoma; Pancreaticoduodenectomy
From: Chinese Journal of General Surgery 2011;26(7):543-545
CountryChina
Language:Chinese
Abstract: Objective To evaluate the preoperative diagnosis and treatment of primary duodenal adenocarcinoma ( PDA). Methods Clinical data of 89 PDA cases undergoing laparotomy from 1985 to 2009 in three hospital in Beijing and Zhengzhou were analyzed retrospectively. Results The prevalence rate of PDA is comparatively low and its clinical manifestations are not specific. The correct diagnostic rate of auxiliary examination were 93% by endoscopy,90% by gastrointestinal X-ray air barium double radiography,82% by MRCP,42% by BUS,70% by CT/MRI. The most common location of the adenocarcinoma(65% ) was at the second portion of the duodenum. Among 67 PDA cases 48 cases underwent pancreatoduodenectomy, 19 cases received segmental deodenectomy. The 5 year's survival rate was 47% and 50% respectively. Conclusions Endoscope and X-ray radiography are mainstays for the diagnosis of PDA. Early diagnosis and radical operation are the key to improve the resection rate and the long term survival.