Diagnosis and treatment for focal nodular hyperplasia of the liver:report of 34 cases

VernacularTitle:肝脏局灶性结节性增生34例诊治分析
Author: Liguo LIU ; Weiqi RONG ; Liming WANG ; Yuxin ZHONG ; Fan WU ; Quan XU ; Yipeng WANG ; Jianxiong WU
Publication Type:Journal Article
Keywords: Liver neoplasms; Focal nodular hyperplasia; Hepatectomy; Diagnosis
From: Chinese Journal of General Surgery 2011;26(6):464-466
CountryChina
Language:Chinese
Abstract: Objective To investigate the clinical features,therapeutic approach and prognosis of focal nodular hyperplasia (FNH) of the liver. Methods Clinical data of 34 FNH patients confirmed by operation were analyzed retrospectively. Results Focal nodular hyperplasia of the liver was found mainly in males (67. 6% ) , Mean nodular size was significantly smaller in men than women. Most of the patients (64.7%) had no significant clinical symptoms. Tumor markers including CA19-9 and A-fetoprotein were within normal range. MRI is helpful to achieve a more accurate diagnosis of the disease, correct preoperative diagnosis rate was 54. 5%. All patients underwent liver resection with no recurrence within 17 - 134 months of follow up. Conclusions FHN of the liver is benign in entity. If a definite diagnosis can be obtained preoperatively, observation follow-up are recommended. Hepatectomy is indicated when there is a suspicion of malignancy.