Diagnosis and surgical treatment of hepatic focal nodular hyperplasia:a report of 63 cases
10.3760/cma.j.issn.1007-631X.2011.06.002
- VernacularTitle:肝脏局灶结节性增生的诊断与外科治疗
- Author:
Weiliang YANG
;
Dongwei ZHANG
;
Haogang ZHANG
;
Huijie JIANG
;
Haomin ZHANG
;
Jianguo ZHANG
;
Jianhua PEI
- Publication Type:Journal Article
- Keywords:
Liver neoplasms;
Focal nodular hyperplasia;
Hepatectomy
- From:
Chinese Journal of General Surgery
2011;26(6):452-455
- CountryChina
- Language:Chinese
-
Abstract:
Objective To summarize the diagnosis and surgical treatment of hepatic focal nodular hyperplasia (FNH). Methods The clinical data of 63 patients with FNH proved by pathology were analyzed retrospectively. Results The disease mainly affected young to middle aged, 50 cases (79. 4% )were of 31-50 years old. Male and female ratio was 2.94: 1. Fifty-six patients (89%) were asymptomatic, 3 cases were HBsAg positive (4.8%). Liver function was basically normal (92. 1%),5 cases (7.9%) were with elevated level of total bilirubin and rGT. AFP, CEA and CA19-9 was all negative. FNH occured as a single node in 95.2% cases, ranging from 1.5 cm to 17 cm in diameter ( average 4. 5 cm). Of these patients, 25 lesions were present in the left lobe, 29 in the right lobe, 6 in the mid lobe, and 3 in the caudate lobe. A big central artery was found in 2 cases (3. 2% ) as found by color Doppler ultrasound. CT scan showed transient immediate enhancement in 96. 8% (61/63) of patients, with central scar in 6 cases. MRI demonstrated early vigorous enhancement in 93. 7% (59/63) of patients, with central scar in 5 cases. All patients underwent surgical resection; including local resection in 34 cases;segmentectomy or hepatectomy in 13 cases; hemihepatectomy in 13 cases. There was no postoperative mortality and major complications. Conclusions FNH is a kind of hepatic benign disease and characteristic of high preoperative misdiagnosis rate (25. 4% ).
